N-Benzyl-2-(3-chloro-4-hydroxyphenyl)acetamide

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N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide

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The title compound, C(14)H(11)ClFNO(2), the phenyl ring (A), the chloro-fluoro-phenyl ring (B) and the central ketone O/C/O group (C) are not coplanar, with dihedral angles B/C = 31.6 (2), A/B = 21.3 (2) and A/C = 50.1 (2)°. The crystal packing is stabilized by N-H⋯O and C-H⋯O inter-actions.

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The structure determination of the title compound, C(16)H(16)ClNO(2), was performed as part of a project on the inter-actions between small organic mol-ecules and proteins. In the crystal structure, the dihedral angle between the two aromatic rings is 16.14 (12)°. The molecules are connected via N-H⋯O hydrogen bonding into chains, which extend in the direction of the b axis.

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4-Chloro-N-(3-chloro­phen­yl)-2-methyl­benzene­sulfonamide

In the title compound, C(13)H(11)Cl(2)NO(2)S, the conformation of the N-H bond in the C-SO(2)-NH-C segment is anti to the meta-Cl atom on the aniline ring and syn to the ortho-methyl group on the sulfonyl-benzene ring. Furthermore, the torsion angle of the C-SO(2)-NH-C segment in the mol-ecule is 80.1 (3)°. The two benzene rings are tilted relative to each other by 70.9 (1)°. In the crystal, pa...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2010

ISSN: 1600-5368

DOI: 10.1107/s1600536810035397